Jonesville Virginia

Upon entering Virginia, US 58 also enters Lee County and becomes Wilderness Road. The divided highway makes a reverse turn heading generally towards the east, in a forested region, before turning east-northeast after to the south of the Wilderness Road entrance to the Cumberland Gap National Historical Park. US 58 crosses over Station Creek, before curving due east through the hamlet of Gibson Station. Past Gibson Station, the highway passes northeast through an area of a rolling hills with homes surrounding either side of the road. It is paralleled by Indian Creek on its southeast side, with the route crossing over its Pendleton Branch, prior to intersecting SR 691 in the village of Wheeler. US 58 continues northeast from Wheeler, before turning due east again while passing along the southern edge of the Wilderness Road State Park. The route crosses Indian Creek twice, before intersecting SR 684 to the southwest of a park and ride lot, and the DeBusk Veterinary Teaching Center of Lincoln Memorial University. The route then dips south through more rural areas of rolling hills, residences, and farmland before turning northeast once more. After passing through some hill cuts with stone sides and crossing over the Roaring Branch of Indian Creek, US 58 reaches the unincorporated town of Ewing. At Ewing, the route reaches its first intersection with a gantry, as its intersection with SR 724 has a blinking yellow light above it. US 58 continues northeast through more rural forests and farmland along the southeastern slope of Poor Valley Ridge, before reaching the unincorporated town of Rose Hill. In Rose Hill, more businesses and houses appear along the edges of the road, and a jersey barrier briefly forms in the median before the road crosses over the White Branch of the Powell River. Beyond the crossing, the median reverts to a grassy surface as US 58 leaves Rose Hill. The route continues to pass more homes, mainly in the traditional style, and businesses, mainly those that are timber shed retailers, before it makes a brief turn to the due east. Here US 58 crosses over Burning Well Road, Hardy Creek, and the railroad line of CSX Transportation (former L&N) leading to the Hagan's Switchback, on a twin-span beam bridge. The route then turns back towards the northeast and crosses the Hugh C. Chance Memorial Bridge. US 58 then makes a curve to the southeast through hilly wooded areas, before crossing over Dry Creek and meeting State Routes 880 and 758 at an intersection. The latter road provides access to the Lee County Airport. Past the intersection, US 58 briefly gains an eastbound climbing lane, before narrowing back to two lanes in each direction. The route continues east before heading northeast through wooded residential areas. Soon US 58 narrows to a two-lane rural road heading east through hilly residential zones entering the town limits of Jonesville, the county seat of Lee County.